Switching Strategy in the Management of Patients with Pulmonary Arterial Hypertension. The REPLACE Study Results
The article is devoted to topical issues of management of patients with pulmonary arterial hypertension and strategies for switching to riociguat therapy in patients with insufficient clinical response against the background of phosphodiesterase type 5 (PDE-5) inhibitors.The role of the NO metabolic pathway in the development of pulmonary arterial