SWITCHING STRATEGY IN THE MANAGEMENT OF PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION. THE REPLACE STUDY RESULTS

Switching Strategy in the Management of Patients with Pulmonary Arterial Hypertension. The REPLACE Study Results

The article is devoted to topical issues of management of patients with pulmonary arterial hypertension and strategies for switching to riociguat therapy in patients with insufficient clinical response against the background of phosphodiesterase type 5 (PDE-5) inhibitors.The role of the NO metabolic pathway in the development of pulmonary arterial

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Two-dimensional-one-dimensional splitting scheme for numerical solution of problems of suspended matter transport in coastal systems

This article discusses the problems of numerical solution of non-stationary convection-diffusion-reaction problems using the model problem of suspended matter transport as an example.In the difference scheme proposed Appetite Control by the authors, at each time layer, the original spatial-three-dimensional problem is split along horizontal directi

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